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Heat Shock Proteins in Cancer - Calderwood, Stuart K.|Sherman, Michael Y.|Ciocca, Daniel R.
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Calderwood, Stuart K.|Sherman, Michael Y.|Ciocca, Daniel R.:

Heat Shock Proteins in Cancer - gebonden uitgave, pocketboek

2007, ISBN: 1402064004

[EAN: 9781402064005], Neubuch, [PU: Springer Netherlands], KREBS (KRANKHEIT) THERAPIE (DIVERSE) FORSCHUNG (MEDIZINISCH, PSYCHOLOGISCH) HEILKUNDE HUMANMEDIZIN MEDIZIN ONKOLOGIE - RADIOONKO… Meer...

NEW BOOK. Verzendingskosten:Versandkostenfrei. (EUR 0.00) moluna, Greven, Germany [73551232] [Rating: 3 (von 5)]
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Calderwood, Stuart K. (Edited by)/ Sherman, Michael Y. (Edited by)/ Ciocca, Daniel R. (Edited by):

Heat Shock Proteins in Cancer - gebonden uitgave, pocketboek

2007, ISBN: 9781402064005

Springer, 2007. Hardcover. New. 1st edition. 398 pages. 9.75x6.75x0.75 inches., Springer, 2007, 6

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Editor-Stuart K. Calderwood; Editor-Michael Y. Sherman; Editor-Daniel R. Ciocca:
Heat Shock Proteins in Cancer (Heat Shock Proteins) - gebonden uitgave, pocketboek

2007

ISBN: 9781402064005

Springer, 2007-11-28. Hardcover. Good., Springer, 2007-11-28

Verzendingskosten: EUR 11.05 Ergodebooks
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CALDERWOOD, STUART K.; SHERMAN, MICHAEL Y.; CIOCCA, DANIEL R. ,:
HEAT SHOCK PROTEINS IN CANCER - gebonden uitgave, pocketboek

2007, ISBN: 9781402064005

kluwer, 2007. 1st. Hardcover. New/New., kluwer, 2007, 6

IND - IndiaVerzendingskosten: EUR 10.03 DELHI BOOK STORE
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Heat Shock Proteins in Cancer - Stuart K Calderwood, Michael Y Sherman, Daniel R Ciocca
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Stuart K Calderwood, Michael Y Sherman, Daniel R Ciocca:
Heat Shock Proteins in Cancer - gebonden uitgave, pocketboek

ISBN: 9781402064005

hardback, [PU: Springer]

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Heat Shock Proteins in Cancer

Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.

Gedetalleerde informatie over het boek. - Heat Shock Proteins in Cancer


EAN (ISBN-13): 9781402064005
ISBN (ISBN-10): 1402064004
Gebonden uitgave
Verschijningsjaar: 2007
Uitgever: Springer-Verlag New York Inc.
406 Bladzijden
Gewicht: 0,777 kg
Taal: eng/Englisch

Boek bevindt zich in het datenbestand sinds 2007-12-01T21:30:38+01:00 (Amsterdam)
Detailpagina laatst gewijzigd op 2021-03-13T02:21:16+01:00 (Amsterdam)
ISBN/EAN: 9781402064005

ISBN - alternatieve schrijfwijzen:
1-4020-6400-4, 978-1-4020-6400-5
alternatieve schrijfwijzen en verwante zoekwoorden:
Auteur van het boek: sherman, erman, calder, daniel, ciocca, michael stuart
Titel van het boek: proteins, cancer, heat, shock the new seven


Gegevens van de uitgever

Auteur: Stuart K. Calderwood; Michael Y. Sherman; Daniel R. Ciocca
Titel: Heat Shock Proteins; Heat Shock Proteins in Cancer
Uitgeverij: Springer; Springer Netherland
400 Bladzijden
Verschijningsjaar: 2007-09-21
Dordrecht; NL
Taal: Engels
213,99 € (DE)
219,99 € (AT)
236,00 CHF (CH)
Available
X, 400 p.

BB; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; Anti-cancer vaccine; Antigen; Cancer therapy; Heat shock proteins; apoptosis; regulation; senescence; surgery; Cancer Biology; Immunology; Biomedical Research; Immunologie; Medizinische Forschung; BC

The Hsp90 Chaperone Machinery Acts at Protein Folding Clefts to Regulate Both Signaling Protein Function and Protein Quality Control.- Implications of Heat Shock Proteins in Carcinogenesis and Cancer Progression.- HSF1: An Emerging Factor In Cancer.- Anti-apoptotic, Tumorigenic and Metastatic Potential of Hsp27 (HspB1) and ?B-crystallin (HspB5): Emerging Targets for the Development of New Anti-Cancer Therapeutic Strategies.- Heat Shock Protein-27 (Hsp-27) in Breast Cancers: Regulation of Expression and Function.- Role of Heat Shock Protein Hsp25/27 in~the~Metastatic Spread of Cancer Cells.- Heat shock chaperone mortalin and carcinogenesis.- Role of Molecular Chaperones in Cell Senescence.- Involvement of Heat Shock Proteins in Protection of Tumor Cells from Genotoxic Stresses.- Hsp70 in Tumors: Friend or Foe?.- Hsp70 and Hsp27 as pharmacological targets in apoptosis modulation for cancer therapy.- Heat Shock Protein 90: The Cancer Chaperone.- Targeting Hsp90 Function to Treat Cancer: Much More to Be Learned.- Small-molecule Hsp90 Inhibitors: Applications in Cancer and Neurodegenerative diseases.- Drugging the Hsp90 molecular chaperone machine for cancer treatment.- Cdc37 and protein kinase folding.- The Elevated Levels of Heat Shock Proteins In Cancer: A Suitable Case For Treatment?.- Hsp70-Based Anticancer Vaccines: Chaperoning The Immune Response.- Piloting of exogenous antigen into cross-presentation pathway by heat shock proteins.
First book to comprehensively cover heat shock proteins in cancer -- an area of high interest Detailed discussion of the role of hsp90 in cancer therapy and drug development Heat shock proteins both as targets for chemotherapy and immunotherapy are examined Unique mechanisms for Hsp in cancer such as apoptosis, senescence and a role in NDA repair are discussed

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