2012, ISBN: 3527330852
[EAN: 9783527330850], Neubuch, [PU: Wiley-VCH GmbH], CHEMIE MEDIZIN BASIC PHARMACOLOGY CHEMISTRY DRUG DISCOVERY & DEVELOPMENT GRUNDLAGEN DER PHARMAKOLOGIE MEDICAL SCIENCE TOXICOLOGY TOXIK… Meer...
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Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - gebonden uitgave, pocketboek
2012, ISBN: 3527330852
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2012, ISBN: 3527330852
[EAN: 9783527330850], Neubuch, [PU: Wiley-VCH GmbH], CHEMIE MEDIZIN BASIC PHARMACOLOGY CHEMISTRY DRUG DISCOVERY & DEVELOPMENT GRUNDLAGEN DER PHARMAKOLOGIE MEDICAL SCIENCE TOXICOLOGY TOXIK… Meer...
Kalgutkar, Amit S.; Dalvie, Deepak; Obach, R. Scott; Smith, Douglas A.; Mannhold, Raimund [Series Editor]; Kubinyi, Hugo [Series Editor]; Folkers, Gerd [Series Editor];:
Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - gebonden uitgave, pocketboek2012, ISBN: 9783527330850
Wiley-VCH, 2012-12-26. Hardcover. Used:Good., Wiley-VCH, 2012-12-26, 0
Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - gebonden uitgave, pocketboek
2012
ISBN: 9783527330850
Wiley-VCH, 2012-12-26. 1. Hardcover. Good., Wiley-VCH, 2012-12-26, 2.5
Reactive Drug Metabolites (Methods and Principles in Medicinal Chemistry) - gebonden uitgave, pocketboek
2012, ISBN: 3527330852
[EAN: 9783527330850], Neubuch, [PU: Wiley VCH 2012-10-24]
2012, ISBN: 9783527330850
gebonden uitgave
Buch, Hardcover, 1. Auflage, [PU: Wiley-VCH], Wiley-VCH, 2012
Bibliografische gegevens van het best passende boek
auteur: | |
Titel: | |
ISBN: |
pharmaceutical companies worldwide. The first chapters trace the development of our understanding of drug metabolite toxicity, covering basic concepts and techniques in the process, while the second part details chemical toxicophores that are prone to reactive metabolite formation. This section also reviews the various drug-metabolizing enzymes that can participate in catalyzing reactive metabolite formation, including a discussion of the structure-toxicity relationships for drugs. Two chapters are dedicated to the currently hot topics of herbal constituents and IADRs.
The next part covers current strategies and approaches to evaluate the reactive metabolite potential of new drug candidates, both by predictive
and by bioanalytical methods. There then follows an in-depth analysis of the toxicological potential of the top 200 prescription drugs, illustrating
the power and the limits of the toxicophore concept, backed by numerous case studies. Finally, a risk-benefi t approach to managing the toxicity risk of reactive metabolite-prone drugs is presented.
Since the authors carefully develop the knowledge needed, from fundamental considerations to current industry standards, no degree in pharmacology is required to read this book, making it perfect for medicinal chemists without in-depth pharmacology training.
Gedetalleerde informatie over het boek. - Reactive Drug Metabolites
EAN (ISBN-13): 9783527330850
ISBN (ISBN-10): 3527330852
Gebonden uitgave
Verschijningsjaar: 2012
Uitgever: Wiley-VCH
386 Bladzijden
Gewicht: 1,017 kg
Taal: Englisch
Boek bevindt zich in het datenbestand sinds 2007-04-28T00:39:27+02:00 (Amsterdam)
Detailpagina laatst gewijzigd op 2023-04-05T14:49:48+02:00 (Amsterdam)
ISBN/EAN: 9783527330850
ISBN - alternatieve schrijfwijzen:
3-527-33085-2, 978-3-527-33085-0
alternatieve schrijfwijzen en verwante zoekwoorden:
Auteur van het boek: scott, deepak, amit, douglas smith, dennis, raimund, hugo kubinyi, gerd folkers, kalg
Titel van het boek: amit
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