2014, ISBN: 9783659271601

[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], The effect of binder type and concentration on six high dose drugs was evaluated. The drugs which are used in this experiment are… Meer...

[ED: Taschenbuch], [PU: LAP LAMBERT Academic Publishing], The effect of binder type and concentration on six high dose drugs was evaluated. The drugs which are used in this experiment are already in market and are available at a very high dose of 500mg and above. Three binders were used in the work at two different user levels. The binders are chosen of different chemistries so in order to predict a optimized formulation for each of the drug. The brittle fracture index of the formulation is calculated by compressing tablets with hole, the hole is an inbuilt defect which will help in propagation of crack into the tablet and enable capping and lamination. The tensile strengths of tablet with hole and without hole are used in calculating BFI. The so calculated BFI is correlated to the dissolution profile of the formulations and the most stable formulation can be formed. Here all the formulations showed excellent results minimum BFI values except Metformin HCl and Paracetamol giving high BFI values indicating susceptibility to Capp or laminate..., DE, [SC: 0.00], Neuware, gewerbliches Angebot, 164, [GW: 262g], Banküberweisung, PayPal, Klarna-Sofortüberweisung, [CT: Sonstiges / Sonstiges]<

2014, ISBN: 3659271608

[EAN: 9783659271601], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware -The effect of binder type and concentration on six high dose drugs was evaluate… Meer...

[EAN: 9783659271601], Neubuch, [PU: LAP LAMBERT Academic Publishing], nach der Bestellung gedruckt Neuware -The effect of binder type and concentration on six high dose drugs was evaluated. The drugs which are used in this experiment are already in market and are available at a very high dose of 500mg and above. Three binders were used in the work at two different user levels. The binders are chosen of different chemistries so in order to predict a optimized formulation for each of the drug. The brittle fracture index of the formulation is calculated by compressing tablets with hole, the hole is an inbuilt defect which will help in propagation of crack into the tablet and enable capping and lamination. The tensile strengths of tablet with hole and without hole are used in calculating BFI. The so calculated BFI is correlated to the dissolution profile of the formulations and the most stable formulation can be formed. Here all the formulations showed excellent results minimum BFI values except Metformin HCl and Paracetamol giving high BFI values indicating susceptibility to Capp or laminate where as Efavirenz and Ciprofloxacin with low BFI values and less susceptible to Capp or laminate. Whereas Metformin has no dissolution failure but Efavirenz has dissolution issues. 164 pp. Englisch, Books<

ISBN: 9783659271601

Paperback, [PU: LAP Lambert Academic Publishing], The effect of binder type and concentration on six high dose drugs was evaluated. The drugs which are used in this experiment are already… Meer...

Paperback, [PU: LAP Lambert Academic Publishing], The effect of binder type and concentration on six high dose drugs was evaluated. The drugs which are used in this experiment are already in market and are available at a very high dose of 500mg and above. Three binders were used in the work at two different user levels. The binders are chosen of different chemistries so in order to predict a optimized formulation for each of the drug. The brittle fracture index of the formulation is calculated by compressing tablets with hole, the hole is an inbuilt defect which will help in propagation of crack into the tablet and enable capping and lamination. The tensile strengths of tablet with hole and without hole are used in calculating BFI. The so calculated BFI is correlated to the dissolution profile of the formulations and the most stable formulation can be formed. Here all the formulations showed excellent results minimum BFI values except Metformin HCl and Paracetamol giving high BFI values indicating susceptibility to Capp or laminate where as Efavirenz and Ciprofloxacin with low BFI values and less susceptible to Capp or laminate. Whereas Metformin has no dissolution failure but Efavirenz has dissolution issues., Pharmacology<

2014, ISBN: 9783659271601

LAP LAMBERT Academic Publishing, Taschenbuch, 164 Seiten, Publiziert: 2014-03-17T00:00:01Z, Produktgruppe: Buch, 0.55 kg, Pharmakologie, Medizin, Kategorien, Bücher, Ingenieurwissenschaft… Meer...

LAP LAMBERT Academic Publishing, Taschenbuch, 164 Seiten, Publiziert: 2014-03-17T00:00:01Z, Produktgruppe: Buch, 0.55 kg, Pharmakologie, Medizin, Kategorien, Bücher, Ingenieurwissenschaft & Technik, Naturwissenschaften & Technik, LAP LAMBERT Academic Publishing, 2014<

2014, ISBN: 3659271608

Kartoniert / Broschiert, mit Schutzumschlag 11, [PU:LAP LAMBERT Academic Publishing]