2012, ISBN: 9783848486458

[ED: Taschenbuch / Paperback], [PU: LAP Lambert Academic Publishing], Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with var… Meer...

[ED: Taschenbuch / Paperback], [PU: LAP Lambert Academic Publishing], Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have been used extensively for solubility enhancement of hydrophobic drug/water insoluble drugs. Diacerein is anthraquinone compound designed to treatment of osteoarthritis. The purpose of this research was to enhance the solubility and therefore dissolution of Diacerein by complexation with -cyclodextrin ( CD) and hydroxyl propyl -cyclodextrin (HP CD).This study represents the formulation of inclusion complex with CD and HP CD by kneading method and their characterization and evaluation of improvement in dissolution profile. Inclusion complex compared to pure drug and physical mixtures, remarkable enhancement in invitro drug release profile in PH 6.8 phosphate buffer was obtained in both inclusion complexes of CD and HP CD, especially with HP CD. Complexation of Diacerein with hydrophilic carriers like CD and HP CD offers a major enhancement in drug solubility., DE, [SC: 0.00], Neuware, gewerbliches Angebot, H: 220mm, 84, Selbstabholung und Barzahlung, PayPal, offene Rechnung, Banküberweisung, Internationaler Versand<

ISBN: 9783848486458

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], Neuware - Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with vario… Meer...

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], Neuware - Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have been used extensively for solubility enhancement of hydrophobic drug/water insoluble drugs. Diacerein is anthraquinone compound designed to treatment of osteoarthritis. The purpose of this research was to enhance the solubility and therefore dissolution of Diacerein by complexation with -cyclodextrin ( CD) and hydroxyl propyl -cyclodextrin (HP CD).This study represents the formulation of inclusion complex with CD and HP CD by kneading method and their characterization and evaluation of improvement in dissolution profile. Inclusion complex compared to pure drug and physical mixtures, remarkable enhancement in invitro drug release profile in PH 6.8 phosphate buffer was obtained in both inclusion complexes of CD and HP CD, especially with HP CD. Complexation of Diacerein with hydrophilic carriers like CD and HP CD offers a major enhancement in drug solubility., DE, [SC: 2.00], Neuware, gewerbliches Angebot, 220x150x5 mm, 84, [GW: 142g], PayPal, offene Rechnung, Banküberweisung, sofortueberweisung.de, Internationaler Versand<

ISBN: 9783848486458

Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have … Meer...

Cyclorins, hydrophilic carriers, are cyclic polysaccharides which have property of forming inclusion complex with various guest molecules with suitable polarity and dimensions. They have been used extensively for solubility enhancement of hydrophobic drug/water insoluble drugs. Diacerein is anthraquinone compound designed to treatment of osteoarthritis. The purpose of this research was to enhance the solubility and therefore dissolution of Diacerein by complexation with -cyclodextrin ( CD) and hydroxyl propyl -cyclodextrin (HP CD).This study represents the formulation of inclusion complex with CD and HP CD by kneading method and their characterization and evaluation of improvement in dissolution profile. Inclusion complex compared to pure drug and physical mixtures, remarkable enhancement in invitro drug release profile in PH 6.8 phosphate buffer was obtained in both inclusion complexes of CD and HP CD, especially with HP CD. Complexation of Diacerein with hydrophilic carriers like CD and HP CD offers a major enhancement in drug solubility. Bücher, Hörbücher & Kalender / Bücher / Sachbuch / Medizin / Pharmazie<

ISBN: 3848486458

Solubility enhancement of diacerin using cyclodextrin ab 48.99 € als Taschenbuch: Solubility and evalution of diacerein using cyclodextrin as hydrophillic carriers. Aus dem Bereich: Büche… Meer...

Solubility enhancement of diacerin using cyclodextrin ab 48.99 € als Taschenbuch: Solubility and evalution of diacerein using cyclodextrin as hydrophillic carriers. Aus dem Bereich: Bücher, Wissenschaft, Medizin, Medien > Bücher, LAP Lambert Academic Publishing<

2012, ISBN: 3848486458

Kartoniert / Broschiert, mit Schutzumschlag neu, [PU:LAP Lambert Academic Publishing]