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2010, ISBN: 9789048168354

Springer. NEAR FINE. Paperback. 2010. Paperback, This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. ., Springer, 2010

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Acceleration and Improvement of Protein Identification by Mass Spectrometry
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9789048168354


At present where protein identification and characterisation using mass spectrometry is a method of choice, this book is presenting a review of basic proteomic techniques. The second part of the book is related to the novel high throughput protein identification technique called the 'molecular scanner'. Several protein identification techniques are described, especially the peptide mass fingerprint with MALDI-MS based method. E.g. ionisation process, matrix available, signal reproducibility and suppression effect, as well as date treatment for protein identification using bioinformatics tools.

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EAN (ISBN-13): 9789048168354
ISBN (ISBN-10): 904816835X
Gebonden uitgave
pocket book
Verschijningsjaar: 2010
Uitgever: Springer-Verlag GmbH
320 Bladzijden
Gewicht: 0,512 kg
Taal: eng/Englisch

Boek bevindt zich in het datenbestand sinds 2012-12-18T20:29:24+01:00 (Amsterdam)
Boek voor het laatst gevonden op 2021-02-05T17:37:18+01:00 (Amsterdam)
ISBN/EAN: 9789048168354

ISBN - alternatieve schrijfwijzen:
90-481-6835-X, 978-90-481-6835-4

Gegevens van de uitgever

Auteur: Willy Vincent Bienvenut
Titel: Acceleration and Improvement of Protein Identification by Mass Spectrometry
Uitgeverij: Springer; Springer Netherland
298 Bladzijden
Verschijningsjaar: 2010-10-19
Dordrecht; NL
Gedrukt / Gemaakt in
Taal: Engels
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
POD
XXII, 298 p.

BC; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Medizinische Forschung; Verstehen; Amino acid; Mass Spectrometry; development; koffie; peptides; protein; proteins; Biomedical Research; BB

At present where protein identification and characterisation using mass spectrometry is a method of choice, this book is presenting a review of basic proteomic techniques. The second part of the book is related to the novel high throughput protein identification technique called the 'molecular scanner'.

Several protein identification techniques are described, especially the peptide mass fingerprint with MALDI-MS based method. E.g. ionisation process, matrix available, signal reproducibility and suppression effect, as well as date treatment for protein identification using bioinformatics tools.

Preface.- Acknowledgements.- List of Contributors.- 1: Introduction: Proteins analysis using mass spectrometry.- 2: Molecular scanner development: Toward clinical molecular scanner for proteome research: Parallel protein chemical processing before and during western-blot.- 3: Quantitation during electroblotting step: Enhanced protein recovery after electrotransfer using square wave alternating voltage.- 4: Signal traitment and virtual imaging (1/2): A molecular scanner to highly automated research and to display proteome images.- 5: Signal traitment and virtual imaging (2/2): Visualization and analysis of molecular scanner peptide mass spectra.- 6: Improvement in the peptide mass fingerprint protein identification (1/2): Hydrogen/deuterium exchange for higher specificity of protein identification by peptide mass fingerprinting.- 7: Improvement in the peptide mass fingerprint protein identification (2/2): MALDI-MS/MS with high resolution and sensitivity for identification and characterization of proteins.- 8: Proteomic and mass spectrometry: Some aspects and recent developments.- 9: Conclusions and perspectives.- Appendix.- Abbreviations used in this book.- Abbreviations for usual amino acids and chemical constants.- Index.


Gives a large overview of protein/peptide chemistry developed over, at least, the last fifty years, e.g. animo or carboxylic groups modifications, charged group derivatisation and stable isotope labelling
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