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ISBN: 9789048175055

ID: 978904817505

Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our time. Nevertheless, our com- protects against transforming defects in oncogenes prehension of the cellular and molecular pathology or tumor-suppressor genes and are here considered of malignant transformation is incomplete. In view as metasuppressor genes. Advances in the molecular of the diverse clinical presentations of various explanations of growth dysregulation, metastasis malignancies, doubts may be raised as to whether it formation, extension of life span, and loss of ma- is appropriate to refer to cancer as one group of dis- tenance of genomic and epigenetic integrity in ease states. The notion of malignant tumors as a cancer suggest models for their causal connection. pathologic and pathophysiologic class of conditions The mechanisms of growth control, senescence, and begs the question for defining criteria that charac- anchorage dependence are linked on the molecular terize all malignant growths, regardless of their tis- level (Chapter 8). In cells that are not fully differ- sue of origin. Toward this goal, the recognition that tiated, the overactivation of oncogene pathways tumor development is caused by the dysregulation also induces the expression of metastasis genes. of growth-controlling genes (oncogenes and tumor- Telomerase, the enzyme that prevents cell sen- suppressor genes) has advanced our mechanistic cence, is expressed in these precursor cells and may understanding of oncology (Chapter 3). However, be further activated by growth factor signaling. Georg F. Weber, Books, Health and Well Being, Molecular Mechanisms of Cancer Books>Health and Well Being, Springer Nature

ISBN: 9789048175055

ID: 9789048175055

Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our time. Nevertheless, our com- protects against transforming defects in oncogenes prehension of the cellular and molecular pathology or tumor-suppressor genes and are here considered of malignant transformation is incomplete. In view as metasuppressor genes. Advances in the molecular of the diverse clinical presentations of various explanations of growth dysregulation, metastasis malignancies, doubts may be raised as to whether it formation, extension of life span, and loss of ma- is appropriate to refer to cancer as one group of dis- tenance of genomic and epigenetic integrity in ease states. The notion of malignant tumors as a cancer suggest models for their causal connection. pathologic and pathophysiologic class of conditions The mechanisms of growth control, senescence, and begs the question for defining criteria that charac- anchorage dependence are linked on the molecular terize all malignant growths, regardless of their tis- level (Chapter 8). In cells that are not fully differ- sue of origin. Toward this goal, the recognition that tiated, the overactivation of oncogene pathways tumor development is caused by the dysregulation also induces the expression of metastasis genes. of growth-controlling genes (oncogenes and tumor- Telomerase, the enzyme that prevents cell sen- suppressor genes) has advanced our mechanistic cence, is expressed in these precursor cells and may understanding of oncology (Chapter 3). However, be further activated by growth factor signaling. Books > Biomedicine Soft cover, Springer Shop

2010, ISBN: 9789048175055

gebonden uitgave, ID: 71793984

Erscheinungsdatum: 10.11.2010, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Molecular Mechanisms of Cancer, Auflage: 2007, Autor: Weber, Georg F., Verlag: Springer Netherlands // Springer Netherland, Sprache: Englisch, Schlagworte: Onkologie // Molekularbiologie // Zellbiologie // Zytologie, Rubrik: Allgemeinmedizin // Diagnostik, Therapie, Seiten: 660, Informationen: Previously published in hardcover, Gewicht: 1584 gr, Verkäufer: averdo Belletristik

2010, ISBN: 9789048175055

ID: 58c775bd0a95e230787948faa936f62a

Letzte Aktualisierung am: 12.01.19 08:48:08 Binding: Taschenbuch, Edition: 2007, Label: Springer, Publisher: Springer, medium: Taschenbuch, numberOfPages: 645, publicationDate: 2010-11-10, authors: Weber, Georg F., languages: english, ISBN: 9048175054 Bücher, Weber, Georg F. -

ISBN: 9789048175055

ID: 9789048175055

Molecular Mechanisms of Cancer Molecular-Mechanisms-of-Cancer~~Georg-F-Weber Medicine>Medical Ref>Spec Procedure Paperback, Springer Netherlands