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Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection - Ian R. Brown
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Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection - pocketboek

ISBN: 9789048178131

[ED: Taschenbuch], [PU: Springer Netherlands], Neuware - With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatme… Meer...

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Ian R. Brown:

Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection - pocketboek

2010, ISBN: 9048178134

[EAN: 9789048178131], Neubuch, [SC: 0.0], [PU: Springer Netherlands], CHAPERONES; HSP; NERVOUSSYSTEM; PARKINSON; PROTEINFOLDING; STRESSPROTEINS; NEURONS, Druck auf Anfrage Neuware -With t… Meer...

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Heat Shock Proteins And The Brain by Alexzander A.A. Asea Paperback | Indigo Chapters
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Heat Shock Proteins And The Brain by Alexzander A.A. Asea Paperback | Indigo Chapters - nieuw boek

ISBN: 9789048178131

With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pres… Meer...

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Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection - pocketboek

2010, ISBN: 9789048178131

Springer, Taschenbuch, Auflage: Softcover reprint of hardcover 1st ed. 2008, 392 Seiten, Publiziert: 2010-10-28T00:00:01Z, Produktgruppe: Buch, Hersteller-Nr.: biography, 1.21 kg, Pharmak… Meer...

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Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection: 3 (Heat Shock Proteins, 3)
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Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection: 3 (Heat Shock Proteins, 3) - pocketboek

2010, ISBN: 9789048178131

Editor: Asea, Alexzander A.A. Editor: Brown, Ian R. Springer, Paperback, Auflage: Softcover reprint of hardcover 1st ed. 2008, 389 Seiten, Publiziert: 2010-10-28T00:00:01Z, Produktgruppe:… Meer...

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Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection

With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis have been termed 'protein misfolding disorders' that are characterized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a therapeutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregation-prone proteins. This book reviews current progress on heat shock proteins in the brain and their implications for neurodegenerative diseases, neuroprotection, aging and control of life span. Key laboratories from major universities around the world contribute chapters that review present research activity and project the field into the future.

Gedetalleerde informatie over het boek. - Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection


EAN (ISBN-13): 9789048178131
ISBN (ISBN-10): 9048178134
Gebonden uitgave
pocket book
Verschijningsjaar: 2010
Uitgever: Asea, Alexzander A.A. Brown, Ian R. Springer
392 Bladzijden
Gewicht: 0,591 kg
Taal: eng/Englisch

Boek bevindt zich in het datenbestand sinds 2008-12-01T05:52:18+01:00 (Amsterdam)
Boek voor het laatst gevonden op 2024-07-09T16:57:53+02:00 (Amsterdam)
ISBN/EAN: 9789048178131

ISBN - alternatieve schrijfwijzen:
90-481-7813-4, 978-90-481-7813-1
alternatieve schrijfwijzen en verwante zoekwoorden:
Auteur van het boek: maria jacques, ian brown
Titel van het boek: brain changes itself, brain diseases, heat


Gegevens van de uitgever

Auteur: Alexzander A.A. Asea; Ian R. Brown
Titel: Heat Shock Proteins; Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection
Uitgeverij: Springer; Springer Netherland
373 Bladzijden
Verschijningsjaar: 2010-10-28
Dordrecht; NL
Gedrukt / Gemaakt in
Taal: Engels
213,99 € (DE)
219,99 € (AT)
236,00 CHF (CH)
POD
XVI, 373 p.

BC; Hardcover, Softcover / Medizin/Klinische Fächer; Neurologie und klinische Neurophysiologie; Verstehen; Chaperones; HSP; Nervous System; Parkinson; Protein folding; Stress proteins; neurons; Neurology; Neuroscience; Biomedical Research; Human Physiology; Pharmacology; Neurowissenschaften; Medizinische Forschung; Physiologie; Pharmakologie; BB; EA

Heat Shock Proteins and Neurodegenerative Diseases.- Chaperones and Polyglutamine Expansion Disorders.- Heat Shock Proteins, Unfolded Protein Response Chaperones and Alzheimer’s Disease.- Cellular and Molecular Mechanisms Underlying Parkinson’s Disease: The Role of Molecular Chaperones.- Heat Shock Proteins as Therapeutic Targets in Amyotrophic Lateral Sclerosis.- The Role of Chaperones and Co-Chaperones in Retinal Degenerative Diseases.- Neuroprotective Features Of Hsp90 Inhibitors Exhibiting Anti-Inflammatory Actions: Implications For Multiple Sclerosis.- Role of HspB1 and HspB8 in Hereditary Peripheral Neuropathies: Beyond the Chaperone Function.- Heat Shock Proteins and Neuroprotection.- Heat Shock Proteins Hsp70 and Hsp27 and Neural Cellular Protection.- Molecular Chaperones and Protection in Animal and Cellular Models of Ischemic Stroke.- Strategies for Conferring Neuroprotection and Countering the High Threshold for Induction of the Stress Response in Motor Neurons.- Use of Viral Gene Delivery Systems to Investigate the Neuroprotective Roles of Hsp70 and Hsp40 Proteins.- Heat Shock Proteins at the Synapse: Implications for Functional Protection of the Nervous System.- Extracellular Heat Shock Proteins and The Nervous System.- Release of Heat Shock Proteins and their Effects When in the Extracellular Space in the Nervous System.- Silencing of Metastasis-associated Gene 1 (Mta1) Stimulates Hsp70 Cellular Release and Neurite extension in Neuroblastoma Cells.- Extracellular Chaperones and Amyloids.- Aging, Control Of Life Span and Expression Of Heat Shock Proteins.- Neural Expression Of Small Heat Shock Proteins Influences Longevity And Resistance To Oxidative Stress.- Mechanistic Links Between Aging and Aggregation-Mediated Proteotoxicity: Role of HSF-1 andDAF-16.- Protein Quality Control and Heat Shock Gene Expression in the Nervous System.- Serum Hsp70 Level as a Biomarker of Exceptional Longevity.- Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection.
Written by leaders in the field of neurodegenerative diseases and neuroprotection Provides up-to-date reviews on the most recent concepts of the role of heat shock proteins in repair and protective mechanisms in the brain Contains chapters with in-depth reviews on i) heat shock proteins and neurodegenerative diseases, ii) heat shock proteins and neuroprotection, iii) extracellular heat shock proteins and the nervous system and iv) aging, control of life span and expression of heat shock proteins

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