2010, ISBN: 9048178134

[EAN: 9789048178131], Neubuch, [SC: 0.0], [PU: Springer Netherlands], CHAPERONES; HSP; NERVOUSSYSTEM; PARKINSON; PROTEINFOLDING; STRESSPROTEINS; NEURONS, Druck auf Anfrage Neuware - With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer's disease, Huntington's disease, Parkinson's disease and amyotrophic lateral sclerosis have been termed 'protein misfolding disorders' that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV). Key basic and clinical research laboratories from major universities and hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Neuroscience, Neurodegenerative Diseases, Molecular Medicine, Aging, Physiology, Pharmacology and Pathology. 392 pp. Englisch, Books

ISBN: 9789048178131

With the prevalence of neurodegenerative diseases on the rise as average life expectancy increases, the hunt for effective treatments and preventive measures for these disorders is a pressing challenge. Neurodegenerative disorders such as Alzheimer''s disease, Huntington''s disease, Parkinson''s disease and amyotrophic lateral sclerosis have been termed ''protein misfolding disorders'' that are char- terized by the neural accumulation of protein aggregates. Manipulation of the cellular stress response involving the induction of heat shock proteins offers a the- peutic strategy to counter conformational changes in neural proteins that trigger pathogenic cascades resulting in neurodegenerative diseases. Heat shock proteins are protein repair agents that provide a line of defense against misfolded, aggregati- prone proteins. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection reviews current progress on neural heat shock proteins (HSP) in relation to neurodegenerative diseases (Part I), neuroprotection (Part II), ext- cellular HSP (Part III) and aging and control of life span (Part IV). Key basic and clinical research laboratories from major universities and hospitals around the world contribute chapters that review present research activity and importantly project the field into the future. The book is a must read for researchers, postdoctoral fellows and graduate students in the fields of Neuroscience, Neurodegenerative Diseases, Molecular Medicine, Aging, Physiology, Pharmacology and Pathology. Books > Health > Medical > Specialties > Laboratory List_Books

2010, ISBN: 9789048178131

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[ED: Kartoniert / Broschiert], [PU: Springer Netherlands], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Written by leaders in the field of neurodegenerative diseases and neuroprotectionProvides up-to-date reviews on the most recent concepts of the role of heat sho, DE, Neuware, gewerbliches Angebot, Softcover, 373, [GW: 599g], 1. Auflage, Banküberweisung, PayPal

2010, ISBN: 9048178134

gebonden uitgave

Softcover reprint of hardcover 1st ed. 2008 Kartoniert / Broschiert Medizinische Forschung, Physiologie, Pharmakologie, Neurologie und klinische Neurophysiologie, Neurowissenschaften, Molekularbiologie, chaperones; Hsp; NervousSystem; Parkinson; proteinfolding; Stressproteins; neurons, mit Schutzumschlag 11, [PU:Springer Netherlands; Springer Netherland]

2010, ISBN: 9048178134

gebonden uitgave

Softcover reprint of hardcover 1st ed. 2008 Kartoniert / Broschiert Physiologie, Pharmakologie, Neurologie und klinische Neurophysiologie, Neurowissenschaften, chaperones; Hsp; NervousSystem; Parkinson; proteinfolding; Stressproteins; neurons, mit Schutzumschlag 11, [PU:Springer Netherlands; Springer Netherland]