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History of Research on Tumor Angiogenesis - Domenico Ribatti
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2004, ISBN: 9789048181568

In 1971, J. Folkman published in the “New England Journal of Medicine” a hypothesis that tumor growth is angiogenesis-dependent. Folkman introduced the concept that tumors probably secret… Meer...

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Ribatti, Domenico:

History of Research on Tumor Angiogenesis - pocketboek

2010, ISBN: 9789048181568

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Erscheinungsdatum: 19.10.2010, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: History of Research on Tumor Angiogenesis, Auflage: Softcover reprint of hardcover 1st ed. 200… Meer...

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History of Research on Tumor Angiogenesis - nieuw boek

ISBN: 9789048181568

Biomedicine; Cancer Research; Oncology; History of Science; Pathology; Cell Biology Monoclonal Antibodies, angiogenesis, tissue, transplantation, tumor growth Books, Springer Nature

In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor. This book compiles the relevant literature of that history and emphasizes the antiangiogenic approach to treat tumors Verzendingskosten:zzgl. Versandkosten., exclusief verzendingskosten

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History of Research on Tumor Angiogenesis - pocketboek

2009, ISBN: 9048181569

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History of Research on Tumor Angiogenesis ab 139.99 EURO Softcover reprint of hardcover 1st ed. 2009 Medien > Bücher

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Domenico Ribatti:
History of Research on Tumor Angiogenesis - pocketboek

2010, ISBN: 9789048181568

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Softcover reprint of hardcover 1st ed. 2009, Softcover, Buch, [PU: Springer]

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History of Research on Tumor Angiogenesis

In 1971, J. Folkman published in the "New England Journal of Medicine" a hypothesis that tumor growth is angiogenesis-dependent. Folkman introduced the concept that tumors probably secrete diffusible molecules that could stimulate the growth of new blood vessels toward the tumor and that the resulting tumor neovascularization could conceivably be prevented or interrupted by angiogenesis inhibitors. Solid and haematological tumors consist of an avascular and a subsequent vascular phase. Assuming that this depends on the release of angiogenic factors, acquisition of angiogenic capability can be seen as an expression of progression from neoplastic transformation to tumor growth and metastasis.Beginning in the 1980's, the biopharmaceutical industry began exploiting the field of antiangiogenesis for creating new therapeutic compounds for modulating new blood vessels in tumor growth. In 2004, Avastin (Bevacizumab), a humanized anti-VEGF monoclonal antibody, was the first angiogenesis inhibitor approved by the Food and Drug Administration for the treatment of colorectal cancer. At present, it has been estimated that over 20,000 cancer patients worldwide have received experimental form of antiangiogenic therapy.This book offers a historical account of the relevant literature. It also emphasizes the crucial and paradigmatic role of angiogenesis as a biological process and the significance of antiangiogenic approach for the treatment of tumors.

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EAN (ISBN-13): 9789048181568
ISBN (ISBN-10): 9048181569
Gebonden uitgave
pocket book
Verschijningsjaar: 2010
Uitgever: Springer-Verlag GmbH
136 Bladzijden
Gewicht: 0,217 kg
Taal: eng/Englisch

Boek bevindt zich in het datenbestand sinds 2012-02-28T12:56:35+01:00 (Amsterdam)
Detailpagina laatst gewijzigd op 2020-04-28T08:50:37+02:00 (Amsterdam)
ISBN/EAN: 9789048181568

ISBN - alternatieve schrijfwijzen:
90-481-8156-9, 978-90-481-8156-8


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