2014, ISBN: 9789401780483
[ED: Softcover], [PU: Springer / Springer Netherlands], Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but n… Meer...
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ISBN: 9789401780483
Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. T… Meer...
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2014, ISBN: 940178048X
2011 Kartoniert / Broschiert Klinische und Innere Medizin, Kardiologie, Angiologie, Bildgebende Verfahren, Neurowissenschaften, RadiatonOncology, mit Schutzumschlag 11, [PU:Springer Net… Meer...
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Razoxane and Dexrazoxane - Two Multifunctional Agents Experimental and Clinical Results - nieuw boek
2014, ISBN: 940178048X
2011 Kartoniert / Broschiert Klinische und Innere Medizin, Onkologie, Kardiologie, Angiologie, Neurowissenschaften, mit Schutzumschlag 11, [PU:Springer Netherlands; Springer Netherland]
Achtung-Buecher.de MARZIES.de Buch- und Medienhandel, 14621 Schönwalde-Glien Verzendingskosten:Versandkostenfrei innerhalb der BRD. (EUR 0.00) Details... |
ISBN: 9789401780483
Paperback, [PU: Springer], Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. the myocardium against anthracyclines or subcutaneous tissue against injuries c… Meer...
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2014, ISBN: 9789401780483
[ED: Softcover], [PU: Springer / Springer Netherlands], Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but n… Meer...
ISBN: 9789401780483
Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. T… Meer...
Razoxane and Dexrazoxane - Two Multifunctional Agents Experimental and Clinical Results - nieuw boek
2014
ISBN: 940178048X
2011 Kartoniert / Broschiert Klinische und Innere Medizin, Kardiologie, Angiologie, Bildgebende Verfahren, Neurowissenschaften, RadiatonOncology, mit Schutzumschlag 11, [PU:Springer Net… Meer...
Razoxane and Dexrazoxane - Two Multifunctional Agents Experimental and Clinical Results - nieuw boek
2014, ISBN: 940178048X
2011 Kartoniert / Broschiert Klinische und Innere Medizin, Onkologie, Kardiologie, Angiologie, Neurowissenschaften, mit Schutzumschlag 11, [PU:Springer Netherlands; Springer Netherland]
ISBN: 9789401780483
Paperback, [PU: Springer], Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. the myocardium against anthracyclines or subcutaneous tissue against injuries c… Meer...
Bibliografische gegevens van het best passende boek
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Gedetalleerde informatie over het boek. - Razoxane and Dexrazoxane - Two Multifunctional Agents: Experimental and Clinical Results Walter Rhomberg Editor
EAN (ISBN-13): 9789401780483
ISBN (ISBN-10): 940178048X
Gebonden uitgave
pocket book
Verschijningsjaar: 2014
Uitgever: Springer Netherlands Core >1 >T
Boek bevindt zich in het datenbestand sinds 2015-01-22T10:54:28+01:00 (Amsterdam)
Detailpagina laatst gewijzigd op 2024-02-17T10:02:02+01:00 (Amsterdam)
ISBN/EAN: 9789401780483
ISBN - alternatieve schrijfwijzen:
94-017-8048-X, 978-94-017-8048-3
alternatieve schrijfwijzen en verwante zoekwoorden:
Auteur van het boek: hellmann, walter hell, rhomberg, kurt walter, walter block
Titel van het boek: razo
Gegevens van de uitgever
Auteur: Walter Rhomberg; Kurt Hellmann
Titel: Razoxane and Dexrazoxane - Two Multifunctional Agents - Experimental and Clinical Results
Uitgeverij: Springer; Springer Netherland
243 Bladzijden
Verschijningsjaar: 2014-11-21
Dordrecht; NL
Gedrukt / Gemaakt in
Taal: Engels
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
POD
XIII, 243 p.
BC; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; Radiaton Oncology; Cancer Biology; Oncology; Radiology; Cardiology; Internal Medicine; Neuroscience; Bildgebende Verfahren; Kardiologie, Angiologie; Klinische und Innere Medizin; Neurowissenschaften; BB
Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms. They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc. The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer´s disease could be stabilized by one or both these drugs.Selectively summarizes the >900 publications on these drugs comprehensive overview But cites most papers Shows where lacunae are
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