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One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms … Meer...

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Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer New Molecular Aspects and their Potential as Targets - Hiscox, Stephen (Herausgeber); Nicholson, Robert I. (Herausgeber); Gee, Julia (Herausgeber)
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Hiscox, Stephen (Herausgeber); Nicholson, Robert I. (Herausgeber); Gee, Julia (Herausgeber):

Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer New Molecular Aspects and their Potential as Targets - pocketboek

2010, ISBN: 9048179017

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Softcover reprint of hardcover 1st ed. 2009 Kartoniert / Broschiert DNA; breastcancer; Cell; hormones; Methylation; therapy; tumor, mit Schutzumschlag 11, [PU:Springer Netherlands; Spri… Meer...

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Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer New Molecular Aspects and their Potential as Targets - Hiscox, Stephen (Herausgeber); Nicholson, Robert I. (Herausgeber); Gee, Julia (Herausgeber)
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Hiscox, Stephen (Herausgeber); Nicholson, Robert I. (Herausgeber); Gee, Julia (Herausgeber):
Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer New Molecular Aspects and their Potential as Targets - pocketboek

2010

ISBN: 9048179017

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Softcover reprint of hardcover 1st ed. 2009 Kartoniert / Broschiert DNA; breastcancer; Cell; hormones; Methylation; therapy; tumor, met couverture 11, [PU:Springer Netherlands; Springe… Meer...

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Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer New Molecular Aspects and their Potential as Targets - Gee, Julia (Herausgeber); Hiscox, Stephen (Herausgeber); Nicholson, Robert I. (Herausgeber)
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Gee, Julia (Herausgeber); Hiscox, Stephen (Herausgeber); Nicholson, Robert I. (Herausgeber):
Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer New Molecular Aspects and their Potential as Targets - pocketboek

2010, ISBN: 9048179017

gebonden uitgave

Softcover reprint of hardcover 1st ed. 2009 Kartoniert / Broschiert DNA; cell; hormones; methylation; therapy; tumor, mit Schutzumschlag neu, [PU:Springer Netherlands; Springer Netherland]

Verzendingskosten:Versandkostenfrei innerhalb der BRD. (EUR 0.00) MARZIES.de Buch- und Medienhandel, 14621 Schönwalde-Glien
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Stephen Hiscox:
Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer - pocketboek

ISBN: 9789048179015

Paperback, [PU: Springer], One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells., Oncology

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Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer by Stephen Hiscox Paperback | Indigo Chapters

One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms of cancer drug resistance have yielded important information highlighting both how tumour cells may escape these therapeutic constraints and that drug resistance may further impinge on tumour cell functions that may ultimately promote an adverse cell phenotype. New targets have been identified with potential therapeutic applications in resistant breast cancer leading to the subsequent evaluation of inhibitors of these targets in preclinical studies. Importantly, there is increasing evidence from such studies demonstrating the benefit of novel combination strategies as potential avenues for future drug regimens.Written by experts in the subject area, this book covers the molecular details and functional consequences of endocrine resistance in breast cancer with particular emphasis on the future applications of novel drug combinations that may be utilized to circumvent resistance and improve anti-tumour effects. This book represents a timely publication in the field of breast cancer research, providing current knowledge in the area of drug resistance and will be important reading material for clinicians and researchers alike.

Gedetalleerde informatie over het boek. - Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer by Stephen Hiscox Paperback | Indigo Chapters


EAN (ISBN-13): 9789048179015
ISBN (ISBN-10): 9048179017
Gebonden uitgave
pocket book
Verschijningsjaar: 2010
Uitgever: Stephen Hiscox
212 Bladzijden
Gewicht: 0,328 kg
Taal: eng/Englisch

Boek bevindt zich in het datenbestand sinds 2011-09-07T18:11:27+02:00 (Amsterdam)
Detailpagina laatst gewijzigd op 2022-08-02T19:33:54+02:00 (Amsterdam)
ISBN/EAN: 9789048179015

ISBN - alternatieve schrijfwijzen:
90-481-7901-7, 978-90-481-7901-5
alternatieve schrijfwijzen en verwante zoekwoorden:
Auteur van het boek: robert nicholson, nichols, gee
Titel van het boek: resistance, the, drugs, potential, anti anti, hormonal


Gegevens van de uitgever

Auteur: Stephen Hiscox; Julia Gee; Robert I. Nicholson
Titel: Therapeutic Resistance to Anti-hormonal Drugs in Breast Cancer - New Molecular Aspects and their Potential as Targets
Uitgeverij: Springer; Springer Netherland
204 Bladzijden
Verschijningsjaar: 2010-10-19
Dordrecht; NL
Gedrukt / Gemaakt in
Gewicht: 0,454 kg
Taal: Engels
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
POD
XII, 204 p.

BC; Cancer Research; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; DNA; breast cancer; cell; hormones; methylation; therapy; tumor; Oncology; Cancer Biology; Oncology; BB

Part 1: OVERVIEW. 1.1 Endocrine resistance in clinical breast cancer; John F Robertson. 1.2 Endocrine resistance in experimental breast cancer; Robert I Nicholson. Part 2: NEW THEMES IN ENDOCRINE RESISTANCE. 2.1 Co-activators / co-repressors and endocrine resistance; Simak Ali. 2.2 Antihormone-induced gene changes: consequences for the development of drug-resistance; Julia Gee. 2.3 Altered signal transduction pathways: impact on ER signalling and expression; Dorraya El-Ashry. 2.4 Epigenetic alterations in DNA methylation in breast cancer; Martin Widschwendter and Heidi Fiegl. 2.5 Antihormone-induced tumour progression; Stephen Hiscox. 2.6 Influence of the tumour microenvironment; Rosemary Walker.2.7 Stem cells; Rob Clarke. Part 3: NEW ADVANCES AND INNOVATIVE THERAPEUTIC APPROACHES. 3.1 DNA profiling; Dennis Slamon. 3.2 Synthetic lethal approaches to target gene discovery; Alan Ashworth. 3.3 Intelligent combination therapies; Stephen Johnston. 3.4 Novel targeting approaches; Paul Workman. 3.5 Future treatment of endocrine-resistant breast cancer: how basic science can guide clinical development; Elizabeth Anderson.

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